Some Serratia entomophila isolates have been successfully exploited in biopesticides on account of their means to set off amber illness in larvae of the Aotearoa (New Zealand) endemic pasture pest, Costelytra giveni. Anti-feeding prophage and ABC toxin subtle virulence determinants are encoded by a 153-kb single-copy conjugative plasmid (pADAP; amber disease-associated plasmid). Regardless of rising understanding of the S. entomophila pADAP mannequin plasmid, little is thought regarding the wider plasmid household.
Correct proper right here, we sequence and analyze mega-plasmids from 50 Serratia isolates that induce variable illness phenotypes contained in the C. giveni insect host. Mega-plasmids are terribly conserved inside S. entomophila, nonetheless present appreciable divergence in Serratia proteamaculans with utterly totally different variants in S. liquefaciens and S. marcescens, doable reflecting area of curiosity adaption. On this evaluation to reconstruct ancestral relationships for a elaborate mega-plasmid system, robust co-evolution between Serratia species and their plasmids have been discovered.
We determine twelve distinct mega-plasmid genotypes, all sharing a conserved gene spine, nonetheless encoding terribly variable accent areas together with virulence elements, secondary metabolite biosynthesis, Nitrogen fixation genes and toxin-antitoxin purposes. We present that the variable pathogenicity of Serratia isolates is principally launched on by presence/absence of virulence clusters on the mega-plasmids, nonetheless notably, is augmented by exterior chromosomally encoded elements. This textual content material is protected by copyright. All rights reserved.
Topological tuning of DNA mobility in entangled selections of supercoiled plasmids
Ring polymers in dense selections are among the many many many most intriguing factors in polymer physics. On account of its pure prevalence in spherical type, DNA has been extensively used as a proxy to overview the important physics of ring polymers in plenty of topological states. Nonetheless, torsionally constrained-such as supercoiled-topologies have been largely uncared for thus far. The applicability of present theoretical fashions to dense supercoiled DNA is thus unknown. Correct proper right here, we deal with this hole by coupling large-scale molecular dynamics simulations with differential dynamic microscopy of entangled supercoiled DNA plasmids.
We uncover that, unexpectedly, bigger supercoiling will enhance the dimensions of entangled plasmids and concomitantly induces an enhancement in DNA mobility. These findings are reconciled as on account of supercoiling-driven uneven and double-folded plasmid conformations that scale back interplasmid entanglements and threadings. Our outcomes counsel a option to topologically tune DNA mobility by means of supercoiling, thus enabling topological administration over the (micro)rheology of DNA-based subtle fluids.
Staphylococcus epidermidis Phages Transduce Antimicrobial Resistance Plasmids and Mobilize Chromosomal Islands
Staphylococcus epidermidis is a main opportunistic pathogen inflicting nosocomial infections that’s notable for its means to type a biofilm and for its excessive bills of antibiotic resistance. It serves as a reservoir of loads of antimicrobial resistance genes that unfold among the many many many staphylococcal inhabitants by horizontal gene swap akin to transduction. Whereas phage-mediated transduction is appropriately studied in Staphylococcus aureus, S. epidermidis transducing phages haven’t been described intimately nevertheless. Correct proper right here, we report the traits of 4 phages, 27, 48, 456, and 459, beforehand used for S. epidermidis phage typing, and the newly remoted phage E72, from a medical S.

epidermidis stress. The phages, labeled contained in the household Siphoviridae and genus Phietavirus, exhibited an S. epidermidis-specific host vary, and collectively they contaminated 49% of the 35 strains examined. An entire-genome comparability revealed evolutionary relatedness to transducing S. aureus phietaviruses. In accordance with this, all of the examined phages have been able to transduction with excessive frequencies as quite a bit as 10-4 amongst S. epidermidis strains from totally utterly totally different clonal complexes. Plasmids with sizes from Four to 19 kb encoding resistance to streptomycin, tetracycline, and chloramphenicol have been transferred.
We offer correct proper right here the primary proof of a phage-inducible chromosomal island swap in S. epidermidis Equally to S. aureus pathogenicity islands, the swap was accompanied by phage capsid transforming; nonetheless, the interfering protein encoded by the island was distinct. Our findings underline the carry out of S. epidermidis temperate phages contained in the evolution of S. epidermidis strains by horizontal gene swap, which might even be utilized for S. epidermidis genetic evaluation.IMPORTANCE Multidrug-resistant strains of S. epidermidis emerge in each nosocomial and livestock environments as important pathogens amongst coagulase-negative staphylococcal species. The evaluation of transduction by phages is important to understanding how virulence and antimicrobial resistance genes unfold in initially commensal bacterial populations.
Multi Fusion-Tagged recombinant Protein 52-Kda containing 16-tags (T-7, HSV, C-myc, VSV-G, Glu-Glu, V5, e-tag, Flag, S-tag, HA, KT3, E2, Au1, Au5, 6xHis-tags) for ELISA/Western |
MFPM52-C |
Alpha Diagnostics |
100 ul |
EUR 286 |
Plasmid Midi Kit II |
K1315-2 |
Biovision |
|
EUR 262 |
Plasmid ezFilter Mega3 Kit |
K1320-2 |
Biovision |
|
EUR 343 |
Plasmid ezFilter Mega6 Kit |
K1321-2 |
Biovision |
|
EUR 370 |
Plasmid ezFilter Mega10 Kit |
K1322-2 |
Biovision |
|
EUR 452 |
Monoclonal Anti-Poly-His (6xhis) (His-tag) IgG |
HISP14-M |
Alpha Diagnostics |
100 ug |
EUR 482 |
ToxOut? Endofree Plasmid Midi Kit |
K1328-2 |
Biovision |
|
EUR 207 |
ToxOut? Endofree Plasmid Maxi Kit |
K1330-2 |
Biovision |
|
EUR 234 |
ToxOut? Endofree Plasmid Mega3 Kit |
K1332-2 |
Biovision |
|
EUR 316 |
ToxOut? Endofree Plasmid Mega6 Kit |
K1333-2 |
Biovision |
|
EUR 370 |
ToxOut? Endofree Plasmid Mega10 Kit |
K1334-2 |
Biovision |
|
EUR 425 |
Plasmid ezFilter Midi Kit I, Centrifuge |
K1316-2 |
Biovision |
|
EUR 262 |
Plasmid ezFilter Midi Kit II, Centrifuge |
K1317-2 |
Biovision |
|
EUR 262 |
Express Plasmid Midiprep Kit (25 min) |
K1323-2 |
Biovision |
|
EUR 262 |
Express Plasmid Maxiprep Kit (25 min) |
K1324-2 |
Biovision |
|
EUR 283 |
ToxOut? Endofree ezFilter Plasmid Midi Kit |
K1329-2 |
Biovision |
|
EUR 207 |
ToxOut? Endofree ezfilter Plasmid Maxi Kit |
K1331-2 |
Biovision |
|
EUR 234 |
ToxOut? Express Endofree Plasmid Midi Kit |
K1335-2 |
Biovision |
|
EUR 234 |
ToxOut? Express Endofree Plasmid Maxi Kit |
K1336-2 |
Biovision |
|
EUR 262 |
pCDH-EF1-CymR-T2A-Puro (plasmid) |
QM200PA-2 |
SBI |
10 ug |
EUR 597 |
|
pCDH-EF1-CymR-T2A-Neo (plasmid) |
QM400PA-2 |
SBI |
10 ug |
EUR 581 |
|
Phospholipid transfer Antibody |
20-abx110096 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Monoclonal Anti-Poly-His (6xhis) (His-tag) antibody, ascites |
HISP11-M |
Alpha Diagnostics |
100 ul |
EUR 482 |
2-Propyl-β-D-glucuronide, 2 mg |
0904-2 |
AthenaES |
2 mg |
EUR 162 |
HER-2 / c-erbB-2 / neu / CD340; Clone HRB2/451 (Concentrate) |
RA0108-C.1 |
ScyTek Laboratories |
0.1 ml |
EUR 125 |
HER-2 / c-erbB-2 / neu / CD340; Clone HRB2/451 (Concentrate) |
RA0108-C.5 |
ScyTek Laboratories |
0.5 ml |
EUR 300 |
Goat Anti-Poly-His (6xhis) (His-tag) IgG, aff pure |
HISP16-A |
Alpha Diagnostics |
100 ug |
EUR 408 |
Goat Anti-Poly-His (6xhis) (His-tag) IgG-FITC conjugate |
HISP16-FITC |
Alpha Diagnostics |
100 ul |
EUR 347 |
Rabbit Anti-Poly-His (6xhis) (His-tag) IgG-IR700DX conjugate |
HISP17-IR7 |
Alpha Diagnostics |
100 ul |
EUR 408 |
IL-2 Interleukin-2 Human Recombinant Protein, His Tag |
PROTP60568-2 |
BosterBio |
Regular: 10ug |
EUR 317 |
Description: Interleukin-2 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 133 amino acids fragment (21-153) having a molecular weight of 20kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. _x000D_ The IL-2 His is purified by proprietary chromatographic techniques._x000D_ |
Rat cholest erolester transfer protein/lipid transfer protein ELISA kit |
E02C0732-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A sandwich ELISA for quantitative measurement of Rat cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse cholest erolester transfer protein/lipid transfer protein ELISA kit |
E03C0732-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A sandwich ELISA for quantitative measurement of Mouse cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse cholest erolester transfer protein/lipid transfer protein ELISA kit |
E03C0732-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A sandwich ELISA for quantitative measurement of Mouse cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse cholest erolester transfer protein/lipid transfer protein ELISA kit |
E03C0732-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A sandwich ELISA for quantitative measurement of Mouse cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog cholest erolester transfer protein/lipid transfer protein ELISA kit |
E08C0732-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A sandwich ELISA for quantitative measurement of Canine cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog cholest erolester transfer protein/lipid transfer protein ELISA kit |
E08C0732-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A sandwich ELISA for quantitative measurement of Canine cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog cholest erolester transfer protein/lipid transfer protein ELISA kit |
E08C0732-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A sandwich ELISA for quantitative measurement of Canine cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat cholest erolester transfer protein/lipid transfer protein ELISA kit |
E06C0732-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A sandwich ELISA for quantitative measurement of Goat cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat cholest erolester transfer protein/lipid transfer protein ELISA kit |
E06C0732-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A sandwich ELISA for quantitative measurement of Goat cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat cholest erolester transfer protein/lipid transfer protein ELISA kit |
E06C0732-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A sandwich ELISA for quantitative measurement of Goat cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit cholest erolester transfer protein/lipid transfer protein ELISA kit |
E04C0732-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A sandwich ELISA for quantitative measurement of Rabbit cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit cholest erolester transfer protein/lipid transfer protein ELISA kit |
E04C0732-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A sandwich ELISA for quantitative measurement of Rabbit cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit cholest erolester transfer protein/lipid transfer protein ELISA kit |
E04C0732-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A sandwich ELISA for quantitative measurement of Rabbit cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig cholest erolester transfer protein/lipid transfer protein ELISA kit |
E07C0732-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A sandwich ELISA for quantitative measurement of Porcine cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig cholest erolester transfer protein/lipid transfer protein ELISA kit |
E07C0732-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A sandwich ELISA for quantitative measurement of Porcine cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig cholest erolester transfer protein/lipid transfer protein ELISA kit |
E07C0732-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A sandwich ELISA for quantitative measurement of Porcine cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat cholest erolester transfer protein/lipid transfer protein ELISA kit |
E02C0732-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A sandwich ELISA for quantitative measurement of Rat cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat cholest erolester transfer protein/lipid transfer protein ELISA kit |
E02C0732-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A sandwich ELISA for quantitative measurement of Rat cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human cholest erolester transfer protein/lipid transfer protein ELISA kit |
E01C0732-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A sandwich ELISA for quantitative measurement of Human cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human cholest erolester transfer protein/lipid transfer protein ELISA kit |
E01C0732-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A sandwich ELISA for quantitative measurement of Human cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human cholest erolester transfer protein/lipid transfer protein ELISA kit |
E01C0732-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A sandwich ELISA for quantitative measurement of Human cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey cholest erolester transfer protein/lipid transfer protein ELISA kit |
E09C0732-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A sandwich ELISA for quantitative measurement of Monkey cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey cholest erolester transfer protein/lipid transfer protein ELISA kit |
E09C0732-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A sandwich ELISA for quantitative measurement of Monkey cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey cholest erolester transfer protein/lipid transfer protein ELISA kit |
E09C0732-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A sandwich ELISA for quantitative measurement of Monkey cholest erolester transfer protein/lipid transfer protein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
BMP-2 Bone Morphogenetic Protein-2 Human Recombinant Protein, Monomer |
PROTP12643-2 |
BosterBio |
Regular: 20ug |
EUR 317 |
Description: Bone Morphogenetic Protein-2 Human Recombinant produced in E.Coli is a monomeric, non-glycosylated, Polypeptide chain containing 115 amino acids (283-396) and having a molecular mass of 13009 Dalton. ;The BMP-2 is purified by proprietary chromatographic techniques. |
PG LIVER 2 EA* |
59423-2 |
Pel-Freez |
2 EA |
EUR 192.24 |
Individual Reaction Mix 2 |
G065-2 |
ABM |
200 reactions |
EUR 167 |
Phospholipid transfer Antibody (Biotin) |
20-abx105774 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Phospholipid transfer Antibody (FITC) |
20-abx107192 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Phospholipid transfer Antibody (HRP) |
20-abx108612 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Phospholipid transfer Polyclonal Antibody |
42297-100ul |
SAB |
100ul |
EUR 333 |
Recombinant Human Relaxin-2 Protein |
PROTP04090-2 |
BosterBio |
25ug |
EUR 317 |
Description: Relaxin-2 is a peptide hormone structurally related to insulin, which is expressed in the placenta, decidua, prostate, and in the ovary during pregnancy. Of the three known relaxin genes, Relaxin-2 is the only relaxin known to circulate in the blood. Relaxin-2 binds specifically to the LGR7 and LGR8 receptors, previously identified as an “orphan” G protein coupled receptors. Signaling by Relaxin-2 through its target receptors enhances the growth of pubic ligaments and ripening of the cervix during birth. Recombinant Relaxin-2 is a nonglycosylated 6.0 kDa disulfide linked heterodimeric protein consisting of a 24 amino acid A-chain and a 29 amino acid B-chain. |
Recombinant Murine IL-2 Protein |
PROTP04351-2 |
BosterBio |
20ug |
EUR 317 |
Description: IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant murine IL-2 is a 17.2 kDa protein, containing 149 amino acid residues. |
Recombinant Human PAI-2 Protein |
PROTP05120-2 |
BosterBio |
10ug |
EUR 317 |
Description: PAI-2 is an inhibitory serpin expressed mainly in keratinocytes, activated monocytes, and placental trophoblasts. It exists predominantly as a 47 kDa nonglycosylated intracellular protein which can be induced to be secreted as 60 kDa glycoprotein. The glycosylated and unglycosylated forms of PAI-2 are equally effective as inhibitors of urokinase-type plasminogen activator (uPA), the only established physiological target of this serpin. PAI-2 has a unique ability to form dormant polymers spontaneously and reversibly under physiological conditions. The physiological relevance of this property, which is neither a consequence of any mutation in the PAI-2 gene nor associated with any known disorder, is still unclear. However, it appears that the formation of intracellular dormant polymers may be important for the controlled release of the inhibitor from PAI-2 producing cells. Plasma levels of PAI-2 are usually low or undetectable, except during pregnancy and in some forms of monocytic leukemia. Secretion of PAI-2 from the placenta normally occurs during the third trimester of pregnancy and accounts for the dramatic increase in PAI-2 levels (up to 250 ng/ml), which are maintained at these levels until postpartum, and then rapidly decline. In addition to its vital role in protecting the placenta from degradation by uPA and/or uPA-activated proteases, PAI-2 has been shown to be essential for the prevention of metastatic spread of neck, lung and breast cancers. The beneficial effect of PAI-2 seen in these studies is presumed to stem from its ability to inhibit uPA-dependent cell dissemination. PAI-2 has also been reported to inhibit keratinocyte proliferation, and to participate in the innate immune response during viral infection. Recombinant human PAI-2 is a 415-residue nonglycosylated protein. |
Recombinant Human MMP-2 Protein |
PROTP08253-2 |
BosterBio |
10ug |
EUR 317 |
Description: Matrix metalloproteinases (MMPs) are a family of endoproteases that require zinc and calcium for expressing catalytic activity. These enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. MMP-2 is a secreted collagenase with specificity toward Type IV, V, VII, and X collagens. Recombinant human MMP-2 is a 62.0 kDa protein containing the entire catalytic N-terminal domain and the C-terminal domain (552 amino acids). |
Recombinant Human BD-2 Protein |
PROTO15263-2 |
BosterBio |
20ug |
EUR 317 |
Description: Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and in some cases, a propeptide sequence. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant human BD-2 is a 4.3 kDa protein containing 41 amino acid residues. |
Anti-ErbB 2/ERBB2 Antibody |
A00010-2 |
BosterBio |
100ug/vial |
EUR 334 |
Anti-Bcl-2/BCL2 Antibody |
A00040-2 |
BosterBio |
100ug/vial |
EUR 334 |
Anti-Angiopoietin-2/ANGPT2 Antibody |
A00370-2 |
BosterBio |
100ug/vial |
EUR 334 |
Anti-Fascin 2/FSCN2 Antibody |
A07840-2 |
BosterBio |
100ug/vial |
EUR 294 |
Bovine KIDNEY WHOLE 2 EA* |
57120-2 |
Pel-Freez |
2 EA |
EUR 174.84 |
Anti-EIF4A1/2/3 Antibody |
A03922-2 |
BosterBio |
100ug/vial |
EUR 334 |
Mouse FGF-2 Recombinant Protein |
R00121-2 |
BosterBio |
5ug/vial |
EUR 259 |
Description: FGF basic (FGF2) is a multipotential fibroblast growth factor that stimulates and supports proliferation, migration and differentiation. Mouse FGF basic (FGF-2) Recombinant Protein is purified FGF basic (FGF-2) produced in yeast. |
On this work, we offer an in depth description of transducing S. epidermidis phages. The intense transduction frequencies of antimicrobial resistance plasmids and the primary proof of chromosomal island swap emphasize the decisive carry out of S. epidermidis phages achieve the following pathogenic potential of host strains. To date, such significance has been attributed solely to S. aureus phages, to not these of coagulase-negative staphylococci. This evaluation furthermore proved that the described transducing bacteriophages symbolize invaluable genetic modification gadgets in S. epidermidis strains the place utterly totally different strategies for gene swap fail.